New Digital Application Notes
New Digital Application Notes

BioAccord Application Workflows

Application-Focused Workflows

The BioAccord LC-MS System comes installed with optimized biopharmaceutical workflows for:

  • Intact Mass Analysis of Proteins & Oligonucleotides
  • Monoclonal Antibody (mAb) Subunit Analysis
  • Released N-Glycan Analysis
  • Peptide Mapping/MAM Analysis

Each workflow provides for compliance-ready data acquisition, processing and reporting with optimized default settings, automated data processing and reporting capabilities, and full audit trail capabilities.


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Intact Mass Analysis

Unifi intact mass analysis workflow

Application Notes:

A Platform Method for the Molecular Mass Analysis of the Light Chains and Heavy  Chains of Monoclonal Antibodies using the BioAccord System

Analysis of Antibody Drug Conjugates (ADCs) by Native Mass Spectrometry on the  BioAccord System

Enabling Routine and Reproducible Intact Mass Analysis When Data Integrity  Matters

Intact Mass Confirmation Analysis on the BioAccord LC-MS System for a Variety  of Extensively Modified Oligonucleotides


Glycan Analysis

Empower glycan analysis workflow

Application Notes:

Released N-linked Glycan Analysis Using the BioAccord System

Increasing Productivity and Confidence for N-linked Glycan Analysis of  Biosimilars Using the BioAccord System

Improving UPLC-FLR-MS N-glycan Analysis of Disulfide-rich Fusion Proteins  Through Optimization of Sample Preparation 

Peptide Mapping/MAM

Peptide Mapping Workflow

Application Notes:

Routine Peptide Mapping Analysis using the BioAccord System

Establishing an Integrated Peptide Attribute Profiling and Monitoring Workflow  for Improved Productivity and Confidence

A Streamlined Compliant Ready Workflow for Peptide-Based Multi-Attribute Method  (MAM)

Biotherapeutic Peptide Mass Confirmation and Impurity Profiling on a SmartMS  Enabled BioAccord LC-MS System

Application-Focused Installation Kits

BioAccord Recommended Consumable Products Cover

See which consumables are included in application-focused installation kits that support common workflows in the BioAccord integrated LC-MS solution.


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